The number of episodes and duration of current IUD use and the risk of ectopic pregnancy

As part of a population-based case-contol study in I I cities in Indonesia in 1989/1990, this study is to assess the risk of ectopic pr(gnancy (EP) associated with current intauterine device (IUD) use. The cases were 560 women with EP. The diagnosis was histopathologically confirmed. Each case was matched by one clinicaLLy pregnant control who was married, lived in the catchment area antl whose age was matched to control by five-year age interval. In-person interviews were conducted to coLlect information regarding dctnographic characteristics, past contraceptive use, and obstetrical-gynecological history. Cases and pregnant controLs, who at the cstinlated date of conception were still using IUD were included for analysis. Five hundred and ten cases and 5 19 pregnant controls were available. Relative to non contraceptive-users, current IUD users who has used IUD for 36-108 months had l4-folds the risk of ucquiring EP [adjusted relative risk (OR) = 14.I ]; 95Vo confdence interval (CI) = j.26 61.061, and among women with only one episode of IIJD use had I I -folds risk of acquiring EP (adjusted RR = I I .79; 95Va CI = 2.68 5 1.85 ). In addition, there was indication o.f increasing risk of EP with the number of episodes as well the duration of curent IUD use (P < 0.001). Therefore, preçnant women yvho at the estimated date ofconception are still using IUD need speciaL attentionfor a higher risk ofacquiring EP.